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If you’re worried about heart health, you’re not alone.According to the CDC, heart disease is the leading cause of death in the United States. While getting regular exercise and keeping your blood pressure at a healthy level can help prevent heart disease, scientists are studying how spice impacts the heart.The spice of chili peppers, to be exact.

You know hot sauce burns. And you know that you love it. But have you ever been in the middle of enjoying some Mad Dog 357 products, and stopped to wonder why? If the scientist inside you is thinking about what causes this pleasurable pain, hang with us to get the answers you’re seeking.

While there are hundreds of types of chili peppers available today, this wasn’t always the case. Before plant breeders developed the Habanero and Carolina Reaper, there were native chili peppers hanging out in the wild. People believe that the original spicy peppers came from low-lying areas of Brazil before they were spread to other areas by birds. Fun fact: birds don’t feel chili peppers’ heat, so they don’t have any problems eating them. Or pooping out their seeds.

In the past, capsaicin’s shown promise in helping to treat a variety of health conditions, from arthritis and headaches to minor muscle sprains and strains. In turns out capsaicin may also have another use. Scientists want to know if capsaicin can be used to help with cannabinoid hyperemesis syndrome. Often called CHS, it’s a condition tied to the long-term daily use of marijuana. Patients with CHS suffer from severe bouts of vomiting, nausea and sometimes, severe abdominal pain.